Program Overview

Zebrafish

Program Goal: To prepare students for a career in biomedical research and innovation by providing both a foundational education in stem cell biology and regenerative medicine and knowledge in how innovative approaches are brought to the biomedical community.

Learning Objectives:
1. Describe foundational concepts in stem cell and developmental biology and translational biology.
2. Explain the principles underlying the equipment, reagents, databases and methods commonly used for research in stem cell biology and regenerative medicine.
3. Develop critical thinking skills by analysis of experimental data in published literature.
4. Dissect the experimental logic underlying studies aimed at elucidating mechanisms of disease and designing therapeutic strategies.
5. Describe current issues and approaches in stem cell biology through writing and oral presentation.
6. Acquire introductory proficiency in stem cell-related technologies and laboratory practices.

Program Curriculum:
Graduation requires completion of 27 units, according to the required Year 1 course schedule outlined below. None of these courses may be substituted or waived.

This program is intended to be completed within one academic year, and does not include a requirement for independent laboratory research or a thesis.

Students may request approval to undertake laboratory research and continuing course work during a second year research internship option, to be completed after the degree is awarded. Students must already be matriculated into the program before making this request, and not all students will be granted this opportunity (selection will be based on academic performance and student research interests, and on availability of laboratory space). During this optional second year, students must enroll in the required Year 2 courses listed below; none of these courses may be substituted or waived.

Required Courses — Fall Year 1

  • DSR 620 Current Topics in Stem Cell Biology and Organogenesis (1 unit) Student-led presentations with faculty-guided discussion of recent literature in the subject of stem cell biology and organogenesis.
  • SCRM 511 Developmental Biology and Human Embryology (4 units) Survey of anatomical, cellular and molecular processes that underlie human development and congenital malformations, with discussion of other species for comparison.
  • SCRM 513 Stem Cells and Regenerative Medicine (4 units) A comprehensive investigation of embryonic, fetal and adult stem cells and the application of stem cell biology to treat disease.
  • SCRM 525 Tools and Techniques in Stem Cell Biology (2 units) Introduces students to classical and cutting-edge techniques used to assess stem cells and regenerating systems.
  • SCRM 555 Writing About Stem Cell Biology and Regenerative Medicine (1 unit) Instruction in writing for various audiences on topics related to stem cell biology and regenerative medicine.
  • SCRM 580 SCRM External Speaker Seminar Series (2 units) Reading and discussion of recent papers by the SCRM speaker of the week, and attendance at the speaker’s seminar.

Required Courses — Spring Year 1

  • DSR 610 Current Topics in Regenerative Medicine (1 unit) Student-led presentations with faculty-guided discussion of recent literature in the subject of regenerative medicine.
  • SCRM 515 Bringing Stem Cells to the Clinic (4 units) Lectures addressing the business, legal, ethical, manufacturing and regulatory aspects involved in moving stem cells or related product into clinical practice.
  • SCRM 522 Biological Imaging in Stem Cell Research (2 units) Theory and practice of using microscopy and flow cytometry in stem cell biology, including sample preparation, digital processing and data analysis. Concurrent enrollment SCRM 524.
  • SCRM 524 Culture and Differentiation of Human Pluripotent Stem Cells (2 units) Classroom and laboratory experience in the techniques for deriving, culturing and differentiating human pluripotent stem cells (hPSCs) and related cell types. Concurrent enrollment SCRM 522.
  • SCRM 580 SCRM External Speaker Seminar Series (2 units) Reading and discussion of recent papers by the SCRM speaker of the week, and attendance at the speaker’s seminar.

Elective Course Requirement (Choose One) — Spring Year 1

  • SCRM 517 Historical and Contemporary Research: HPSCs (2 units) Historical and contemporary stem cell research using hematopoietic stem cells as a model system.
  • SCRM 519 Historical and Contemporary Research: Neural Stem Cells (2 units) Focuses on historic achievements in stem cell research and how contemporarily, research and its related technological advances have fostered breakthroughs the understanding of NSCs.
  • SCRM 521 Historical and Contemporary Research: Tissue Development Engineering (2 units) Focuses on the components of cell, molecular biology, and basic tissue development to comprehend its uses within the realm of synthetic biology and cellular/tissue engineering.

Required Courses — Fall Optional Research Year 2

  • DSR 620 Current Topics in Stem Cell Biology and Organogenesis (1 unit) Student-led presentations with faculty-guided discussion of recent literature in the subject of stem cell biology and organogenesis.
  • SCRM 580 SCRM External Speaker Seminar Series (2 units) Reading and discussion of recent papers by the SCRM speaker of the week, and attendance at the speaker’s seminar.
  • SCRM 590 Independent Research (1-4 units) Independent research conducted under the guidance of faculty in the Department of Stem Cell Biology and Regenerative Medicine.

Required Courses — Spring Optional Research Year 2

  • DSR 610 Current Topics in Regenerative Medicine (1 unit) Student-led presentations with faculty-guided discussion of recent literature in the subject of regenerative medicine.
  • SCRM 580 SCRM External Speaker Seminar Series (2 units) Reading and discussion of recent papers by the SCRM speaker of the week, and attendance at the speaker’s seminar.
  • SCRM 590 Independent Research (1-4 units) Independent research conducted under the guidance of faculty in the Department of Stem Cell Biology and Regenerative Medicine.